Phenobarbital will reduce the extent or influence of bortezomib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch. fluconazole will increase the amount or influence of bortezomib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. bortezomib will improve the amount or result of atogepant by influencing hepatic/intestinal enzyme CYP3A4... https://smedleyi554uep7.like-blogs.com/profile