You will find a launch of norepinephrine through the descending inhibitory bulbospinal neurons that binds to alpha-two-receptors during the dorsal horn to lessen afferent pain transmission and produce analgesia. Thus, medicines like clonidine that concentrate on alpha-two receptors can affect the transmission of pain. For those who get dizzy https://whatischronicpain90008.mybuzzblog.com/11740297/the-smart-trick-of-onolidine-that-nobody-is-discussing