Pentobarbital will decrease the level or effect of losartan by affecting hepatic enzyme CYP2C9/10 metabolism. Minor/Significance Unknown. pentobarbital will decrease the level or effect of quinine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. pentobarbital will decrease the level or effect of bexarotene by affecting hepatic/intestinal enzyme CYP... https://socialislife.com/story5808963/tutto-ci%C3%B2-che-riguarda-what-is-nembutal-pentobarbital