Usually this stress is 0.25 inches of drinking water column, but is often elevated or decreased as the process requires. Isolators need to be periodically leak tested to ensure their integrity and forestall escape on the decontamination agent. Leak testing can be done by different approaches like pressure decay https://tailinscitech.wordpress.com/2026/01/16/applications-and-benefits-of-tailin-containment-isolator-for-handling-high-potency-materials/